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O-Town (slang) Type: noun, slang Pronunciation: /O-town/ What does O-Town mean and stand for? Orlando, Florida. O-Town in songs: “It’s similar to O-Town, in the Southern Peninsula” – Nas, The Ghetto. “I’m Bow Weezy, prince of the O-town” – Bow Wow, I Think They Like Me (Remix). “”Sak pase” to Zoe Pound, for lifers in […]