Pruno (slang) Type: noun, slang Pronunciation: /pru-no/ What does Pruno mean? Wine made by inmates in prison. Example sentence: “The inmates partied with pruno.” Pruno in songs: “Now I’m chillin’ in my cell lookin out the window Drinkin’ pruno, smokin’ indo” – Mac Dre, I’ve Been Down. “By now Grandpa went crazy and my Uncle […]